The mHealth Messaging to Motivate Quitline use and Quitting among Persons Living with HIV (PLWH) in Vietnam (M2Q2-HIV) study is an adaptation of our current computer-tailored smoking cessation intervention in Vietnam (NCI/Fogarty 1R01TW010647). We seek to promote underused government resources for public health (quitline) and nicotine replacement therapy (NRT) among PLWH in a sustainable manner.
Our Specific Aims are:
Aim 1: Adapt the Vietnam M2Q2 peer messaging, computer-tailored texting intervention for PLWH smokers:
1a: Conduct qualitative interviews with key stakeholders (providers (n=5) and community health workers (n=10)) and PLWH smokers (n=20), assessing stigma associated with HIV and/or concomitant substance use, training gaps, tobacco use, and perceived cessation support needs.
1b: Using the same 20 PLWH smokers, develop peer messages using a co-writing strategy.
1c: Conduct 3-4 mini-pilots (n=15) to test and refine study protocols and technology.
Aim 2: Randomize 750 PLWH smokers and follow them for six months to evaluate effectiveness and process outcomes of M2Q2-HIV compared with a minimal texting control.
H1 (Primary): Intervention PLWH Smokers will have higher rates of carbon monoxide (CO) verified, six-month, seven-day point prevalence cessation than comparison smokers.
H2: Intervention PLWH Smokers will have higher self-efficacy scores than comparison smokers.
H3: Intervention PLWH Smokers will have higher quitline and NRT use than comparison smokers.
H4: Specific measured processes (e.g., self-efficacy; quitline; NRT use) will partially mediate observed intervention effectiveness.
Aim 3: Prepare for wide-spread national dissemination by assessing acceptability and contextual factors guided by the Practical, Robust Implementation and Sustainability Model (PRISM) using qualitative interviews with key stakeholders (n=15) and PLWH smokers (n=30).
Our primary hypothesis is that smokers in the PLWH intervention group will have higher rates of smoking cessation, compared with the smoker in the comparison group.
The project has been approved by the government and is being implemented in Hai Phong and Quang Ninh in collaboaration with DoHs, CDCs and 24 OPCs in two provinces.